FIRST COMPARISON OF THROMBOELASTOGRAPHY VERSUS LIGHT TRANSMITTANCE AGGREGOMETRY TO DEFINE HIGH PLATELET REACTIVITY

Platelet reactivity assessment with VerifyNow®: substitute or complement for light transmission aggregometry?

Platelet aggregation inhibition is mandatory for patients undergoing percutaneous coronary intervention (PCI) [1]. High on-treatment plate-let reactivity is an important independent risk factor for the occurrence of thrombotic and ischemic events after PCI [2]. Some point of care platelet aggregation assays are currently used in daily practice as a substitute for more expensive and time consumi...

Comparison between a new platelet count drop method PL-11, light transmission aggregometry, VerifyNow aspirin system and thromboelastography for monitoring short-term aspirin effects in healthy individuals.

Platelet function has been described by many laboratory assays, and PL-11 is a new point-of-care platelet function analyzer based on platelet count drop method, which counts platelet before and after the addition of agonists in the citrated whole blood samples. The present study sought to compare PL-11 with other three major more established assays, light transmission aggregometry (LTA), Verify...

Comparison of Aggregometry with Flow Cytometry for the Assessment of Agonists´-Induced Platelet Reactivity in Patients on Dual Antiplatelet Therapy

Data on the agreement between aggregometry and platelet activation by flow cytometry regarding the measurement of on-treatment platelet reactivity to arachidonic acid (AA) and adenosine diphosphate (ADP) are scarce. We therefore sought to compare three platelet aggregation tests with flow cytometry for the assessment of the response to antiplatelet therapy. Platelet aggregation in response to A...

Influence of hematocrit and platelet count on impedance and reactivity of whole blood for electrical aggregometry.

Previous studies have shown that differing qualities of blood specimen seem to influence whole blood electrical aggregometry (WBEA), making it difficult to standardize the method. The aim of this study was to investigate the impact of hematocrit (HCT) and platelet count (PLC) on in vitro platelet aggregation in citrated whole blood (CWB) in order to compensate for their possible effects on impe...

Platelet Aggregometry and Aspects of Residual Platelet Reactivity in Patients with Coronary Artery Disease Treated with Aspirin and Clopidogrel